DoubleClick Ad Exchange is improving its 
pretargeting system by creating a new user interface and API resource to configure the inventory your bidder sees. These changes will only impact your RTB campaigns; non-RTB campaigns will continue to be managed as they were before.
Upgrades will begin in mid-July 2014 and all accounts will be upgraded by the end of September 2014. 
The new functionality has been added to the v1.3 REST API but will be read-only until your account has been upgraded. For additional information, please review the new 
resource reference and 
pretargeting guide.
Note that once your account has been upgraded you will still have access to the 
SOAP API for reporting, budgeting and non-RTB campaigns, but you will no longer be able to use it for pretargeting. If you need the ability to manage your pretargeting settings via the API, then you must use the latest 
AdX REST API.
If you have questions about these upcoming changes please contact your account manager. For questions about the Ad Exchange Buyer API, check out the 
Ad Exchange Buyer API forum. Follow our 
Google+ page for other announcements and updates.
Dean Lukies, DoubleClick Ad Exchange Buyer API Team